Ongeveer 14 uur geleden - Rijksoverheid
Senior wetenschappelijk onderzoeker / topexpertRijksinstituut voor Volksgezondheid en MilieuHet centrum Gezondheidsbescherming is volop in ontwikkeling. Als en…
Project descriptionCrystallization of water into ice is lethal to most organisms and detrimental to many soft materials. Freeze-avoidant fish living in polar seas evolved to tackle this problem with an unusual coping strategy. They produce ...
Crystallization of water into ice is lethal to most organisms and detrimental to many soft materials. Freeze-avoidant fish living in polar seas evolved to tackle this problem with an unusual coping strategy. They produce 'antifreeze' proteins that block the growth of embryonic ice crystals within a narrow temperature range known as the 'thermal hysteresis gap' enabling survival under extreme conditions. In this project you will design and implement single molecule imaging methods to unravel how antifreeze proteins work and to better understand the functionality of biomimetic polymeric antifreezes developed for materials science and biomedical applications.
We seek highly talented, motivated, and enthusiastic candidates with a PhD degree in Biophysics, Biological Soft Matter, Bionanotechnology, (Bio)Physical Chemistry, Molecular (Life) Sciences, or related discipline. The successful candidate has experience with single molecule imaging and/or force spectroscopy and protein biophysics; knowledge of crystallization and microfluidics is preferred. Furthermore, good communication skills, fluency in English, and a strong motivation to do original, fundamental research in an interdisciplinary team are essential. An interview and a scientific presentation are part of the selection process.
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